Webb7 dec. 2024 · Triple-negative breast cancer (TNBC) is difficult to treat due to its aggressive nature. It often responds initially to chemotherapy but is the most common breast cancer to recur; when it recurs, it is more resistant to chemotherapy, making it less responsive and more challenging to treat. WebbKunskapsbank för cancervården. I kunskapsbanken finns alla nationella vårdprogram, …
Diagnosis and Therapy of Triple-Negative Breast Cancer (TNBC ...
Webb14 nov. 2024 · So zeigte sich, dass eine zusätzliche platinhaltige Therapie im neoadjuvanten Setting zu einer Steigerung der pCR beim TNBC führt. 14–16 Ein weiterer Erfolg wurde in der I-SPY2-Studie erzielt, in welcher eine Kombinationstherapie aus Veliparib und Carboplatin zusätzlich zur Standard-NST in PhaseII bei verschiedenen … WebbTriple negative breast cancer (TNBC) comprises 15-20 percent of all breast cancers, but … relations logic
Full article: Triple-negative breast cancer: promising prognostic ...
Webb29 aug. 2024 · TNBC is a highly heterogeneous cancer with specific mutations and … WebbTNBC is typically observed in young AA women and Hispanic women who carry a mutation in the BRCA1 gene. TNBC is characterized by a distinct molecular profile, aggressive nature and lack of targeted therapies. The purpose of this article is to review the current and future novel signalling pathways as therapeutic approaches to TNBC. Webb4 mars 2024 · The application of RNA nanotechnology to deliver anti-miRNA has become a new technology for TNBC therapy. These therapeutic RNA nanoparticles bind to the CD133 receptor to inhibit the expression of miR21 and up-regulate the expression of downstream tumor suppressor genes PTEN and PDCD4, which can significantly inhibit the … relations love fair in new york crossword