Web5 apr. 2024 · Self-administered subcutaneous monthly dose with a potential best-in-class efficacy profile . LONDON, UK I April 04, 2024 I Positive results from the ETESIAN Phase IIb trial showed AZD8233 (an investigational antisense oligonucleotide [ASO], also known as ION449) met the primary endpoint at 50 mg with 73% (95% confidence interval [CI]: … Web23 sep. 2024 · ION449 (AZD8233) met primary endpoint in Phase 2b SOLANO study for patients with hypercholesterolemia ION449 will not advance into Phase 3 development based on pre-specified criteria CARLSBAD, Calif., Sept. 23, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. ( Nasdaq: IONS) today announced that

Antisense Pipeline Ionis - Ionis Pharmaceuticals, Inc.

Web23 sep. 2024 · The primary objectives of this study were to assess the efficacy, safety and tolerability of ION449 (AZD8233) as compared with placebo. About ION449. ION449 (AZD8233) dosed once monthly via subcutaneous administration, is an investigational medicine that uses Ionis' advanced LIgand-Conjugated Antisense (LICA) technology … Web4 apr. 2024 · ION449 (AZD8233) dosed once monthly via subcutaneous administration, is an investigational medicine that uses Ionis' advanced LIgand-Conjugated Antisense (LICA) technology platform. croma kalikapur

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Web5 apr. 2024 · ION449 is being developed by AstraZeneca as part of a collaboration between Ionis and AstraZeneca. About ION449 ION449 (AZD8233) dosed once monthly via subcutaneous administration, is an investigational medicine that uses Ionis' advanced LIgand-Conjugated Antisense (LICA) technology platform. Web13 nov. 2024 · ION449, also known as AZD8233 for subcutaneous administration and AZD6615 for oral administration, is being developed as part of a collaboration between … Web5 apr. 2024 · AstraZeneca, together with its partner Ionis Pharmaceuticals, has unveiled positive results for AZD8233, an investigational antisense oligonucleotide therapy, from … cromakalim翻译