WebRetinal abnormalities may occur during or following the subretinal injection of LUXTURNA, including macular holes, foveal thinning, loss of foveal function, foveal dehiscence, chorioretinal atrophy, and retinal hemorrhage. Monitor and manage these retinal abnormalities appropriately. Do not administer LUXTURNA in the immediate vicinity of … WebMar 1, 2015 · Foveal thickness was measured and retinal tomography was observed and investigated. If no abnormality was noted on retinal tomography, a repeat examination using multiple horizontal and vertical scans was performed. Patient characteristics and visual function and OCT results were collected.
Foveal Thinning & Retinal Scar: Causes & Reasons - Symptoma
WebAcute foveal thinning with unchanged perifoveal function in one patient and macular hole in a second suggests foveal vulnerability to the subretinal injections. Longer observation intervals will help establish the significance of the minor differences in sensitivities and rate of disease progression observed between intervention and control eyes. WebFeb 3, 2024 · Variable foveal thinning and macular hole formation after subfoveal injections were first observed in the RPE65 gene therapy clinical trials and have since been documented in other studies that have treated the central retina with subretinal delivery of different vectors. 102, 112, 114, 135, 136 Targeting the parafoveal retina may be … bateau skyfall
FOVEAL SPARING INTERNAL LIMITING MEMBRANE PEELING FOR …
WebNov 17, 2024 · Foveal thinning implied a long-standing ischemic environment and atrophy, which may increase patient susceptibility to poor visual and anatomical outcomes. Due to simultaneous ERM and ILM peeling during the SO removal surgery and the absence of a residual premacular membrane, mechanical trauma during membrane peeling may have … WebInner foveal thinning and intracellular alpha-synuclein were demonstrated in the retina in Parkinson disease. While pathognomonic alpha-synuclein is associated with embryonic … WebThe foveal lesion was a subtle abnormal depression with variably associated retinal cystic changes or a surrounding yellow ring. Of 95 eyes with involutional macular thinning, … bateau smoke amsterdam