Ctgf emt
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Ctgf emt
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WebMay 15, 2013 · Furthermore, expression of CTGF in lung epithelial cells or treatment with exogenous CTGF also induced EMT-like changes in vitro. Overall, our results provide … WebMar 22, 2024 · The present study further investigated whether CTGF promotes EMT, as well as ECM synthesis, by treating RPE cells with different concentrations of CTGF (15, 30 and 60 ng/ml) using RT-qPCR and western blotting ().The results demonstrated that the mRNA and protein (Fig. 1D and E) expression levels of the epithelial markers ZO-1 and E …
WebSep 9, 2015 · Expression of CTGF highly correlates to EMT markers. EMT is a fundamental process in organ fibrosis and has been demonstrated to be closely related to cancer progression . To see whether CTGF has any connection with EMT, we first performed a co-expression analysis between CTGF and EMT markers in clinical breast tumors and a … WebMar 10, 2024 · miR-133b ameliorates cardiac fibrosis [8,9,10], reduces TGF-β1-mediated EMT of bladder smooth muscle epithelial cells , and directly targets the connective tissue growth factor (CTGF) [9, 11]. Whether CTGF is a target involved in miR-133b-mediated inhibition of EMT of renal tubular epithelial cells remains unclear, and studies are …
WebFeb 7, 2024 · The epithelial–mesenchymal transition (EMT) is a phenomenon in which epithelial cells differentiate into mesenchymal cells and is widely recognized as a mechanism of malignant transformation of cancer, in which epithelial-derived cancer cells acquire migratory properties and invade blood vessels. ... Fn1, and Ctgf. HUVECs … WebDec 1, 2024 · Connective tissue growth factor (CTGF), also known as cellular communication network factor 2 (CCN2), is one of the most widely studied members of the CCN family. CTGF is highly expressed in many ...
WebJan 1, 2024 · CCN2, also known as connective tissue growth factor (CTGF), is a key mediator of tissue remodeling and fibrosis (Lipson et al., 2012). ... Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro. J. Cell Sci., 126 (2013), pp. 2164-2175.
WebMay 28, 2009 · We and others have shown that hepatocytes substantially synthesize connective tissue growth factor (CTGF/CCN2) during culture and in injured liver and are likely to be the major cellular source of CTGF in the liver. 1, 2 CTGF is a 36- to 38-kDa, cysteine-rich, heparin-binding and secreted protein that was first identified in the … diamond shop ukWebCourse Title: Advanced Skills for EMS providers. Units: 4. Notes: Course Number: ENGL 1A + 1AS. Course Title: University-Parallel Reading and Composition + Support. Units: 4-6. … diamond shores hoaWebJan 12, 2015 · Overexpression of connective tissue growth factor (CTGF) in AT II cells induces EMT. Cell morphology of AT II cells from ( a ) control … cisco switch change vlan on port cliWebJan 12, 2015 · Overexpression of connective tissue growth factor (CTGF) in AT II cells induces EMT. Cell morphology of AT II cells from ( a ) control and ( b ) CTGF+ mice after being cultured for 96 h (scale bar ... cisco switch check memory usageWebCommission on Accreditation of Allied Health Education Programs (CAAHEP) 1361 Park Street. Clearwater, FL 33756. (727) 210-2350. ( www.caahep.org) Committee on … cisco switch change port nameWebNov 8, 2024 · Upregulation of YY1 was associated with EMT and pro-fibrotic phenotype induced by TGF-β treatment. Targeted knockdown of YY1 abrogated the EMT induction by TGF-β treatment. ... Furthermore, lung epithelial cells produce pro-fibrotic mediators including connective tissue growth factor (CTGF), platelet derived growth factor … diamond shores hutchinsonWebCTGF and β-catenin are involved in the EMT of podocytes in diabetes. CTGF mediates high-glucose induced EMT through activation of β-catenin in podocytes. CTGF inhibition … cisco switch change password for user